Search on: PROSTATIC INTRAEPITHELIAL NEOPLASIA 
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Descriptor English:   Prostatic Intraepithelial Neoplasia 
Descriptor Spanish:   Neoplasia Intraepitelial Prostática 
Descriptor Portuguese:   Neoplasia Prostática Intraepitelial 
Synonyms English:   Neoplasia, Prostatic Intraepithelial  
Tree Number:   C04.557.470.200.240.500
Definition English:   A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer. 
Indexing Annotation English:   /blood supply /chem /second /secret /ultrastruct permitted; coord IM with PROSTATIC NEOPLASMS (IM); DF: PROSTATIC INTRAEPITHELIAL NEOPL
History Note English:   96 
Allowable Qualifiers English:  
BS blood supply BL blood
CF cerebrospinal fluid CI chemically induced
CH chemistry CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SC secondary
SE secretion SU surgery
TH therapy US ultrasonography
UL ultrastructure UR urine
VE veterinary VI virology
Record Number:   32640 
Unique Identifier:   D019048 

Occurrence in VHL:
 

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